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The Gates Foundation’s $2.5 billion pledge is historic, but founders say it’s only a starting point. Here’s how they want the money to be spent, and why more bold action is still needed.

Women’s Health Founders React to Gates Foundation $2.5 Billion Pledge Image

Women’s Health Founders React to Gates Foundation $2.5 Billion Pledge

A sweeping new CMS initiative, backed by the White House, will create a secure, interoperable app store for Medicare, offering startups unprecedented access to health data and a massive user base.

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Medicare's New App Store Opens a $1 Trillion Market to Health Startups

Reggie Swift, PhD, Rubix LS Founder and CEO, is revolutionizing clinical research by designing inclusive, data-driven clinical trials that reflect the diversity of real-world patients, helping healthcare innovators, CROs, and agencies transform health equity and outcomes.

How Rubix LS is Reengineering Clinical Trials HERO image

How Rubix LS is Reengineering Clinical Trials for Real-World Impact image

How Rubix LS is Reengineering Clinical Trials for Real-World Impact

Pitch competitions can boost credibility, sharpen your strategy, and connect you with investors—but they also demand time and focus. Here's how to decide if they’re worth it for your startup.

Should You Enter a Pitch Competition? What Healthcare Startups Need to Know HERO image

Should You Enter a Pitch Competition? What Healthcare Startups Need to Know

Endpoints that reflect real-world value to patients can help startups improve enrollment and retention, and boost commercial success.

How Patient-Centered Trials Can Improve Biotech ROI

Monica Cepak is redefining what it means to lead in healthcare. She’s transforming Wisp into a fearless, first-to-market platform for women’s sexual and reproductive health, normalizing taboo topics, and launching new verticals.  

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Monica Cepak’s Playbook for Scaling Wisp as a Brand Women Actually Trust

As Series B capital gets harder to secure, companies raise more in earlier rounds to reach value milestones.

‘Barbell Effect’ Reshapes Funding for Healthcare Entrepreneurs Image HERO

‘Barbell Effect’ Reshapes Funding for Healthcare Entrepreneurs

Protein misfolding is the foundation of a multi-billion-dollar drug class reshaping treatment for Alzheimer’s and ALS, thanks to innovators like Jeffery Kelly, PhD.

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How One Scientist’s Misfolded Protein Breakthrough is Saving Lives

Funding experts reveal how healthcare entrepreneurs’ messaging can build trust, communicate value, and position your startup for long-term success.

What Not to Say to Investors: 5 Messaging Mistakes That Can Derail Your Pitch

Nell Smircina of Novastone Capital Advisors and Vivian Cervantes of CORE IR explain how founders should approach valuation and why getting it wrong can cost you more than funding.

What Every Healthcare Startup Needs to Know About Valuation

Newly released FDA complete response letters offer healthcare entrepreneurs insight into why drug applications fail and how to avoid the same mistakes.

What Startups Can Learn from FDA ‘No’ Letters

Open-source biological datasets Boltz-2 and Tahoe-100M are helping resource-strapped healthcare entrepreneurs and academic scientists accelerate drug discovery using AI but without the high data costs.

How Public Data Fuels the Next Wave of Drug Innovation

Leaders from NYCEDC, Ally Bridge Group and Hunter College share how mentorship drives innovation, sharpens leadership skills, and expands professional networks.

Mentoring Pays Off: How Guiding Others Can Boost Your Own Career

Faced with shrinking budgets, academic and industry life science researchers are making strategic partnerships their top priority.

Why Scientists and Startups are Doubling Down on Partnerships in 2025

OFFOR Health and LOUD Capital founder Navin Goyal, MD, breaks down five proven B2B models, from subscriptions to data licensing, and reveals the biggest mistake healthcare entrepreneurs make when selling to providers and payers.

5 B2B Revenue Models Every Healthcare Startup Should Consider

Nell Smircina of Novastone Capital Advisors and Vivian Cervantes of CORE IR explain how choosing the right mix of advisors can support your company’s mission and milestones.

Your Healthcare Startup Needs an Advisory Board—Here’s How to Build One That Matters

16-year-old entrepreneur Khartik Uppalapati, co-founder of the RareGen Youth Network, is combining AI innovation and advocacy to reshape how rare diseases are diagnosed and addressed globally.

How a Teen Turned His Rare Diagnoses into a Rare Movement

CMS’s new Cell and Gene Therapy Access Model allows states to offer sickle cell gene therapies through federally negotiated contracts, reshaping CGT market for startups and rare disease therapeutics.



New Federal Program Expands Access to Gene Therapies for Sickle Cell and More

Scaling a startup is more than just growth. Founders from G9 Ventures, Evvy, Inflect Health, and Kindbody offer six tips to preserve trust, brand, and purpose as your company gets larger.

Scaling Smart: How to Grow Women’s Health Startups 

Despite a historic slump in biotech IPOs and venture funding, three women-led exits break through in a tough 2025.

Startups Face Bleak Funding While Women-Led Firms Score Rare M&A Wins

AI startups attracted most of the new digital health money in the first half of 2025, as investors focus on scaling proven technologies.

AI-Powered Companies Dominate 2025 Digital Health Funding

Ali Chappell, PhD, RD, Co-Founder and CEO of Lilli Health, shares how she transformed her experience with PCOS into a data-driven nutrition and wellness company offering services and app to have “a dietitian in your pocket.”


How a PCOS Diagnosis Fueled One Founder’s Mission to Disrupt Women’s Health

Robyn Riseberg, MD, shares how she founded Boston Community Pediatrics as the first nonprofit private pediatric practice to bring integrated healthcare to children in Boston.

Reimagining Pediatric Care: How One Nonprofit is Setting a New Standard for Health Equity

Strong mentorships can accelerate your entrepreneurial journey. Experts from NYCEDC, Ally Bridge Group, and Hunter College share how to communicate, build trust and get the most out of a mentor relationship.

6 Tips to Maximize Your Mentor Relationship

The Supreme Court’s decision upholding preventive care coverage under the Affordable Care Act signals a stable, growing market for healthcare startups and entrepreneurs.

Supreme Court Upholds Preventive Care Mandate — What It Means for Healthcare Innovation

Founders behind Teal Health, Proov, Sunny, and Bloomlife reveal lessons from their FDA experiences, from unexpected reclassifications to trial redesigns to funding gaps.

How MedTech Startups Navigate the FDA: Lessons from Women’s Health Innovators

The EU’s top health official said reforms will make Europe more attractive for drug developers as FDA changes create industry uncertainty.

Europe Makes Bold Bid to Attract Biotech Amid FDA Uncertainty

In a move praised by advocates and physicians, the FDA eliminated post-treatment safety restrictions for CAR T therapies based on real-world data, potentially setting a precedent for regulatory flexibility for cell and gene therapies.

FDA Lifts Key Barriers to Immunotherapies Access, Signaling Regulatory Shift

The International Center for Professional Development connects underrepresented scholars and African entrepreneurs with healthcare industry mentors, training and opportunities.

How Mentoring Programs Fuel Pipeline of Healthcare Entrepreneurs 

The shortage of anti-obesity medications is sending patients to gray markets while healthcare innovators look for longer-term solutions beyond of GLP-1s.

How Entrepreneurs are Looking Beyond GLP-1s for Obesity Innovations

When VCs say no, founders are tapping alternative sources, from academic accelerators and angel investors to strategic industry partnerships and mission-aligned family offices, to bring solutions to market.


Beyond VC: 6 Ways to Fund Your Healthcare Startup

Founders behind Elektra Health, Frame Fertility, Gabbi, and OOVA share how trial, error and trust shaped their GTM journeys.

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4 Women’s Health Entrepreneurs Reveal Go-to-Market Strategies

Mentors are trusted allies whose valuable experience-based wisdom can open doors for healthcare entrepreneurs navigating from startup to longterm success.

5 Smart Ways to Find a Mentor Who Moves Your Healthcare Career Forward

NYU Langone’s Marc Sedam shares how, amid sweeping federal cuts to scientific research, some U.S. universities are quietly rewriting the funding playbook for moving discoveries from lab to market.

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Universities Step Up as Translational Funders Amid NIH Uncertainty

CEO Mary Beth Cicero says women’s health startups face hurdles even with novel ideas and real-world demand.

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Breakthrough IUD Faces Familiar Funding Barrier in Women’s Health

Healthcare industry executives at BIO paint a picture of optimism for the sector's future amid policy changes and technological disruptions.

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6 Executives on How Resilience, Not Retreat, Defines the Healthcare Year Ahead

Ernst & Young’s latest report shows biotech investors remain cautious in 2025, but innovation and partnerships offer path for a rebound.

Biotech Seeks Turnaround as Investors Focus on Fundamentals

Entrepreneurs Jenny Carillo, Roya Pakzad, and Mike Satow advise on how to healthcare companies can prepare for acquisitions, from bankers and buyers to IP and partnerships. 

How to Exit Smart:  7 Mistakes Healthcare Founders Should Avoid 

Despite reductions and restructuring, the FDA is strong and on track to meet its goals, FDA Commissioner Martin Makary, MD, said at BIO.

FDA Commissioner Pushes Aggressive Overhaul Amid Biotech Uncertainty

Jennifer Celio Li of Samsung, Mika Miyake of Garmin Health, and Nichole Young-Lin of Google share how women’s health startups can collaborate with Big Tech.

How to Win Over Big Tech: Partnership Playbook for FemTech Founders

New data from Cure reveals how healthcare entrepreneurs are betting on AI to reshape drug development, advance rare disease treatments, and reduce clinical and financial barriers to innovation.

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AI Emerges as Healthcare’s Bright Spot Amid Industry Upheaval

The FDA held a listening session with cell and gene therapy scientists, advocates and entrepreneurs to learn how to improve the regulatory process.

FDA Industry Panel Pushes for Faster Cell and Gene Therapy Reviews

The FDA is setting new priorities designed to bring innovative healthcare products to market faster, though concerns about political interference at federal science agencies complicate the picture.

FDA Shares New Priorities and ‘Proactive’ Approach to Working with Developers

Oriana Papin-Zoghbi, Co-Founder and CEO of AOA Dx, created a blood test to detect ovarian cancer at early stages when women’s survival rate is higher.

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How an Entrepreneur is Fulfilling the Need for Early Detection of Ovarian Cancer

Equal Research Day highlights the persistent disparity of women in medical research and elevates leaders working to change that. Cure spotlights seven women shaping a more equitable future in healthcare innovation.

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7 Women Advocates Who Drive Gender Equity in Health Research

A new wave of studies and startups are pushing blood-based cancer tests into clinics, yet access and cost challenges remain.

Blood Tests Offer Earlier, Personalized Detection of Cancer’s Return image

Blood Tests Offer Earlier, Personalized Detection of Cancer’s Return

Five healthcare entrepreneurs share pivotal mentorship advice that helped them navigate career shifts and overcome scientific setbacks.

What My Mentor Taught Me: Healthcare Entrepreneurs Share Lessons Learned

The MAHA Commission, chaired by HHS Secretary Robert F. Kennedy, Jr., critiques current U.S. policies and spotlights four drivers of “the sickest generation," including industry influence, overmedicalization, environment exposures and systemic failures.

‘MAHA’ Reports U.S. Children’s Health Issues, Calls for Strategic Realignment

The U.S. faces a tipping point in science and innovation, with top experts urging bold reforms to reverse declines in research funding, talent, and global influence.

Reclaiming U.S. Scientific Leadership: A Wake-Up Call for Innovators

How can improving care options lead to unlocking profitability? Women’s health entrepreneurs from Daré Biosciences, Organon, and Willow offered insights at the 2025 SiS New York Conference.

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6 Ways to Make Women’s Health Profitable

Reginald Swift, PhD, CEO of Rubix

The FDA is moving swiftly to overhaul its drug and device review process with the help of AI, announcing plans to implement these tools across every agency center by the end of June.

FDA Sets Aggressive AI Rollout to Speed Drug Reviews

Charisse Dean, Managing Director Advisory, KPMG

New reports from Jefferies and J.P. Morgan offer a split-screen view of biotech’s rough start and its potential recovery in the second half of 2025.

Best or Worst of Times for U.S. Healthcare? Analysts Split on Outlook

While the biopharma market continues to struggle financially, companies focused on digital health and AI are gaining traction with funders.

How AI-Powered Apps Opened $5.3B in New Deals for Healthcare Entrepreneurs in Q1 2025

Ascertain uses agentic AI to streamline burdensome workflows of healthcare case managers and drive better, more cost-efficient patient care.

How Ascertain Scales AI to Cut Hospital Admin Work, Improve Patient Care

Harvard and MIT respond to federal crackdown on international students and research funding.

Trump Administration Action Against Harvard Sparks Backlash, Scientific Talent War

Wandercraft launches its first U.S. clinic in New York City, offering people with spinal cord injuries, stroke, and other neurological conditions personalized neurorehabilitation using its self-balancing Atalante X exoskeleton.

Wandercraft’s ‘Walk in New York’ Clinic Opens for Hands-Free Exoskeleton Therapy

From AI-powered reproductive health tools to WhatsApp care help women worldwide, despite continued social barriers to use and financial challenges for FemTech developers.

Digital Health Tools Advance Women’s Autonomy, But Gaps Remain

Former President Biden’s metastatic prostate cancer diagnosis highlights a new era of precision medicine, as healthcare startups and oncologists develop more accurate diagnostics and less invasive treatments to combat the disease’s deadliest forms.

Biden’s Diagnosis Brings Urgency to Prostate Cancer Innovation

After the collapse of the Haven venture, JPMorgan Chase launched Morgan Health, investing $250 million into startup-driven solutions aimed at transforming how employers deliver and pay for healthcare.

JPMorgan's $250M Bet on Fixing Employer Healthcare

A growing number of state legislatures are proposing laws that would limit and even criminalize mRNA medicines, just as the technology is starting to provide new approaches to diseases ranging from ALS to MD and from pancreatic cancer and HIV/AIDS. 

Proposed mRNA Bans Alarm Scientists and Startups

Lux Capital's initiative offers money, mentorship and migration pathways to keep scientific discoveries alive amidst rising international competition for America's innovators.

Lux Capital Launches $100M ‘Helpline’ for U.S. Scientists

The executive order could harm innovative research and development, but could also alleviate financial burdens on patients.

Trump’s Drug Pricing Executive Order Splits Biopharma Leaders

As biopharmas report first quarter earnings, executives are being asked to respond to the Trump administration’s many changes to the business environment, regulatory scene and domestic manufacturing.

Drugmakers Brace for Trump-Era Shifts on Tariffs, Manufacturing and Regulation

During the 2025 XSeed Award ceremony, a panel of biotech investors, policy experts, and founders offered hard-earned advice to early-stage entrepreneurs navigating a volatile funding landscape.

Experts Urge Healthcare Startups to Stay Bold, Focused, and Patient-Centered

Two NYC-based startups, GenKardia and Sidereal Therapeutics, have each won a $250,000 XSeed Award to support moving promising preclinical research of novel therapies for kidney and heart disease forward toward commercialization.

$250K XSeed Awards Granted to Minority- and Women-Led Startups Advancing New Drugs 

After a career championing entrepreneurs and science policy at BIO, E. Cartier Esham, PhD, launched her own firm to help healthcare innovators navigate Washington, DC, and shape the future of medicine

From Bench Scientist to Policy Powerhouse: E. Cartier Esham’s Entrepreneurial Pivot

Small businesses can secure non-dilutive funding through the NIH SBIR program to develop healthcare technologies and services that overcome barriers to care for populations experiencing health disparities.

NIH Offers $10 Million in Grants for Startups Tackling Health Disparities

Sidereal Therapeutics is developing a potential first-in-class biologic to prevent acute kidney injury from progressing to chronic disease by targeting iron overload at its source.

Novel Biologic Aims to Stop Kidney Damage Before it Turns Chronic

Adiutrix Therapeutics is developing a novel targeted therapy for the lung-stiffening disease known as idiopathic pulmonary fibrosis, offering the potential to be safer and more potent than current treatments.

How a Startup Targets a Deadly Lung Disease

Vasocure is advancing targeting therapies to prevent arteriovenous graft (AVG) stenosis for patients on kidney dialysis that may also unlock new treatments for atherosclerosis.

How One Company Targets Dialysis Complications with Novel Therapy

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From Hibernating Bears to Humans: A New Therapeutic Path for Heart Failure 

XSeed Award finalist Aggregate Biosciences is developing precision diagnostics and therapeutics aiming to transform treatment for Alzheimer’s, type 2 diabetes, and other amyloid-related diseases.

How This Company Is Fighting Alzheimer's With a New Approach to Amyloid

Three key takeaways from AdvaMed's new report provide suggestions for companies developing new medical technologies that rely on AI.

How AI Medtech Entrepreneurs Can Tackle Policy, Payment and Privacy Pitfalls

The FDA’s new plan to phase out many animal studies is already reshaping drug R&D as startups and pharma teams adopt digital and human-cell platforms.

FDA Roadmap Accelerates High-Tech Alternatives to Animal Tests

Technological innovation and clinical research are opening new doors for entrepreneurs to tackle spine surgery’s diagnostic gaps, improve outcomes, and reduce healthcare costs.

How Entrepreneurs Could Disrupt Spine Surgery

A public garden opening next month in San Francisco pays tribute to young people who died of metastatic breast cancer. The first such U.S. memorial also exposes a stubborn truth: new drugs have not erased the disease’s deadliest form.

‘They Keep Dying Young’: Memorial Garden to Honor Lives Lost to Breast Cancer

Sunbird Bio's platform aims to address a $20 billion global neurology diagnostics market to test for Alzheimer’s, Parkinson’s, ALS and more. 

How Sunbird Bio is Changing Brain Disease Diagnoses  

Companies and medical centers are increasingly looking at how inserting computer chips in the brain can help patients recover from a variety of conditions, in a market expected to hit $12 billion in the next decade.

From Thoughts to Reality – the Rise of Brain-Computer Interface Tech 

Ambient AI scribes are rapidly transforming healthcare practices and reportedly significantly reducing physician burnout while maintaining documentation quality, though financial returns remain unclear.

Doctors Embrace AI Scribes as Solution for Burnout

Scientists are scrambling to manage surging costs as President Trump's sweeping tariffs on imported laboratory equipment begin to bite.

Trump Tariffs Strain Science Research Budgets for Lab Equipment

First Patients Join Study of Wandercraft Home-Use Exoskeleton

A new analysis finds that cell and gene therapies are twice as likely to win FDA approval, but commercial uptake remains slow due to cost, infrastructure and delivery challenges.

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Despite Twice the FDA Success Rate, Gene Therapies Still Miss Patients

CEO Marissa Fayer draws on her engineering background to lead DeepLook Medical and advises women’s health startups to think big, stay strategic, and seek broader investor support.

Women’s Health CEO Shares Advice on Raising Funds: Be Direct

A new federal report warns that America’s biotech leadership is slipping behind China, calling for a $15 billion investment plan to boost innovation and protect national interests.

U.S. Falling Behind in Biotech, Government Warns

U.S. Urged to Invest $15 Billion in Biotech to Counter China

Targeted investments in overlooked areas of women’s health could unlock massive financial and societal returns.

5 Smart Investments  for the Future of Women’s Health

Bioworkshop is revolutionizing neurological disease research with an award-winning biochip platform that models complex brain conditions like Parkinson’s to accelerate drug discovery.

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How Bioworkshop is Building a Better Brain Model for Parkinson’s 

Tia Health is reshaping women’s healthcare experiences with primary care in-person clinics that offer collaborative, holistic patient-centric approach.

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How Tia Stays Competitive in a Crowded Healthcare Landscape

While biopharma struggles attracting investors, AI, non-opioid pain medications, cell and gene therapies and metabolic diseases are still finding funding. 

How AI Moonshots Nailed Biotech Funding in Bleak Quarter

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