Top Institutes and Centers
Every institute and center on this list represents the best in U.S. biomedical research. We ranked 60 institutions on their translational performance, using criteria built to reflect how these organizations operate and fund their research.
Hospital for Special Surgery
Ranked 31st among the 60 biomedical institutes in the Cure Innovation Index, Hospital for Special Surgery is based in New York, New York. The institute's Entrepreneurial Readiness stands above the midpoint of its category and represents its strongest domain; Research Capabilities and Market Translation reflect more moderate positioning.
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Children's Hospital of Los Angeles
Children's Hospital of Los Angeles ranks 32nd among the 60 biomedical institutes evaluated in the Cure Innovation Index. Located in Los Angeles, California, the institute performs in the upper tier for Research Capabilities and Entrepreneurial Readiness, with comparatively lower activity in Market Translation.
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The Methodist Hospital Research Institute
The Methodist Hospital Research Institute, located in Houston, Texas, ranks 33rd among the 60 biomedical institutes and centers assessed by the Cure Innovation Index. The institute places 12th in Entrepreneurial Readiness, the strongest of its three domain positions, with an environment that includes biomedical entrepreneurship training and an incubator and accelerator program.
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Henry Ford Hospital
Henry Ford Hospital ranks 34th among the 60 biomedical institutes evaluated by the Cure Innovation Index. Based in Detroit, Michigan, the institute presents a translation-leaning profile: entrepreneurial readiness is its strongest area, placing 12th in the category, while research capabilities and market translation remain in developing territory.
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Lurie Children's Hospital
Lurie Children's Hospital ranks 35th among the 60 biomedical institutes in the Cure Innovation Index and is based in Chicago, Illinois. Its profile shows above-average standing in both research capabilities and entrepreneurial readiness, with market translation as a developing area.
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St. Jude Children's Research Hospital
St. Jude Children's Research Hospital ranks 36th among the 60 biomedical institutes in the Cure Innovation Index, based in Memphis, Tennessee. Its research capabilities place seventh in the category, a strong showing that reflects the hospital's focus on pediatric disease science.
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Roswell Park Comprehensive Cancer Center
Roswell Park Comprehensive Cancer Center ranks 37th among biomedical institutes in the Cure Innovation Index. Located in Buffalo, New York, it demonstrates strong research capabilities, placing among the top-ranked institutes in that domain.
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Buck Institute for Research on Aging
The Buck Institute for Research on Aging ranks 38th among the 60 biomedical institutes evaluated in the Cure Innovation Index. Located in Novato, California, the institute centers its mission on aging biology and the diseases of later life.
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Fox Chase Cancer Center
Fox Chase Cancer Center, based in Philadelphia, Pennsylvania, ranks 39th among the 60 biomedical institutes assessed by the Cure Innovation Index. Its research capabilities rank 10th in the category, reflecting a profile built around scientific investigation.
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Geisinger Medical Center
Geisinger Medical Center ranks 40th among the 60 biomedical institutes in the Cure Innovation Index. Located in Danville, Pennsylvania, the institute is a large integrated health system with research programs across its clinical enterprise.
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Cure Innovation Index Methodology
From a pool of more than 6,000 institutions, the top 303 were ranked using two dozen indicators — from scientific foundation and lab infrastructure to patents, products, and partnerships — drawn from more than a dozen federal and commercial databases, an original audit of all institutions, and surveys of more than 3,300+ scientists, industry leaders, and biomedical experts.
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Innovation isn't a single moment — it's an entire ecosystem. The Index evaluates institutions across two dozen indicators, grouped in three core domains that reveal the full picture of what it takes to turn groundbreaking science into real-world impact.
Insights From the Cure Innovation Index




